Sentence examples for generating lymphocyte from inspiring English sources

Another attractive hypothesis that had been proposed to explain singular expression is somatic recombination into an active locus, analogous to the role of recombination in generating lymphocyte diversity and singular expression of T-cell receptors and immunoglobulins.

Thus, consistent tolerance to multiple minor-H mismatches was only achieved with WT donors that were able to generate lymphocyte chimerism in the recipients.

Thymomas are rare neoplasms of the TECs that often generate lymphocytes that mature into CD4+ and CD8+ T-lymphocytes.

Thirty-six male C57B1/6 mice were X-irradiated whole body with 3 Gy to generate lymphocytes with dicentric chromosomes to study the persistence of these lymphocytes in the spleen and peripheral blood to estimate the life span of mature B- and T-cells.

It is likely that a multicomponent, adaptive immune system arose with the first vertebrates, as invertebrates do not generate lymphocytes or an antibody-based humoral response.

On the other hand, CD45− EB cells resemble precursors found in paraaortic splanchnopleura (P-Sp) and AGM region which generate lymphocytes and also lack CD45 [28], [28].

We assessed whether the peripheral blood of normal HLA-matched siblings of patients with melanoma could be used to generate lymphocytes with antimelanoma activity for adoptive immunotherapy after allogeneic blood or marrow transplantation.

In contrast, multiple minor-H or MHC mismatched transplants did not consistently induce natural tolerance unless they carried chimerism generating passenger lymphocytes.

Thus, we conclude that bone marrow actively participates in destructive arthritis by generating B-lymphocyte-rich bone marrow lesions and inducing endosteal bone formation.

They induced the proliferation of allogeneic lymphocytes in a mixed-lymphocyte reaction, and could generate cytotoxic lymphocytes, with the ability to lyze tumor cells in an antigen-specific manner.

For each chain, an antigen binding V domain is generated during lymphocyte development as a consequence of rearrangements of variable (V), diversity (D), and joining (J) genes.