The results suggest that this new design possesses synergistic potential of immunotherapy combined with established macromolecular therapy; moreover, a conventional chemo-agent could be utilized to generate highly effective ADCs and to achieve lower risk of off-target toxicity.
Therefore, leaf tissues would need to generate highly effective antioxidants and free radical scavengers to aid in quenching and removing the ROS and to minimize the photosensitization-induced oxidative damage.
Since ∼60 bp hairpin RNAs should be capable of providing a substrate for at least three catalytic reactions involving Dicer, we have examined the possibility of introducing three distinct non-contiguous target sequences that, if processed by Dicer, are capable of generating highly-effective independent siRNA species.
Two-step tests revealed that the addition of water is effective for generating highly active Mo sulfide catalyst from ATTM, but water itself does not promote catalytic conversion.
The discipline of microbial consortia engineering possesses a widely accepted potential to generate highly novel and effective bio-catalysts for applications from biofuels to specialty chemicals to enhanced mineral recovery.
The transformation of overpressured till into hyperconcentrated slurries in subglacial channels may have generated a highly effective erosional tool for selective overdeepening and sculpting of bedrock substrates.
Not only did the competition itself generate several highly effective message ads, but the "news" element of the contest itself and the predictable indignation with which it was greeted in some circles also helped garner exposure in the mainstream media.
This L. monocytogenes strain generated a highly effective antitumor T-cell response, providing a basis for the development of this vaccine platform in patients with liver metastases.
This catalysis is of biological significance since it is crucial to iron and bile metabolism, and also generates a highly effective antioxidant in bilirubin (from biliverdin via bilirubin reductase).
DG technology provides a cost-effective approach to rapidly generate highly accurate genotyping data.
Despite the tremendous efforts spent so far, generating potent and highly effective CTLs remain a major roadblock for disease control (prevention and therapies).
