Sentence examples for generating efficacious from inspiring English sources

Alternative platforms to construct ZFNs have since emerged, and these show variation in speed, site selection and success in generating efficacious ZFNs (Sander et al., 2011; Gupta et al., 2012; Bhakta et al., 2013).

On the basis of preclinical and early clinical results, the question is not whether cocktails of mAbs have a bright future as therapeutics, but rather what platform is able to reproducibly and cost effectively generate efficacious concoctions that are approvable by the regulatory authorities.

Taken together, these data demonstrate that binding of antigens through one or more LysM sequences to nonliving, nonrecombinant bacterial particles can generate efficacious subunit vaccines.

"Shaping" the immune responses elicited against Aβ is requisite toward generating an efficacious and safe outcome; this can be achieved by minimizing the possibility of deleterious inflammatory reactions in the brain as observed in clinical testing of Aβ peptide/adjuvant-based modalities.

Indeed, the human immune system itself can safely be assumed to be the best in generating highly efficacious antibodies and these antibodies are most likely superior to those generated from mice or using phage display.

However, this property of ESCs also poses a unique challenge of having to generate therapeutically efficacious quantity of appropriate cell types without being contaminated by potentially deleterious cell types.

Vaccination generated an efficacious protective effect, but no expression differences were detected at 2 weeks post vaccination.

This study suggests that conversion of celecoxib into its isomeric iodo-[I]-analogues is a useful approach for generating novel and efficacious agents for COX-2-targeted SPECT imaging of inflammation.

These viruses have also been well characterized, extensively studied for primate responses, and have been found to be efficacious in generating antibodies.

This understanding will allow selection and design of toxin immunogens with a view to generating a safer and more efficacious pan-specific antivenom against any mamba envenomation.

For MS, unraveling the pathogenetic events behind the disease subtypes represents a major goal for understanding and generating the most appropriate and efficacious treatment for that disease phenotype.