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The alterations in osseous remodeling lead to the increase or decrease of the osseous mass, generating damage to the osseous micro-architecture, which increases the risk of fracture.
In this model of their action, chemotherapeutic drugs drive cell death by generating damage signals at their locus of action (eg DNA damage), and these signals become integrated at Bcl-2 family protein containing complexes where the decision to undergo apoptosis is taken and signalled to apoptosis effector molecules.
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Cadet, J. & Douki, T. Oxidatively generated damage to DNA by UVA radiation in cells and human skin.
Cadet, J., Douki, T. & Ravanat, J.L. Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells.
Cadet, J., Douki, T., Ravanat, J. L. & Di Mascio, P. Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation.
Iron promotes formation of hydroxyl radicals by the Fenton reaction, subsequently leading to potential oxidatively generated damage of nucleic acids.
The other is a sampling-based method that repeatedly generates damage scenarios in the time period of interest.
There's a "swivel seat" so you never need reverse and extra large bumpers to "ensure that any accidental scrapes and bumps whilst parking don't generate damage".
The localized heating temperature generates damage in concrete and partial evaporation of the matrix in the GFRP rebars without causing the collapse of the element.
It is necessary to first generate damage at the element level from the section damage at the fiber level discussed in the previous section.
Our data point towards two ways by which misfolded NTS1 may be generated: Damage by exposure to buffer components and by close contact of the receptor to the neurotensin affinity resin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com