Sentence examples for generating and screening from inspiring English sources

DuPont developed its product through painstaking research, systematically generating and screening millions of compounds for the desired effect.

In order to identify genes involved in the early essential stages of pathogenesis, namely adhesion and colonization, Signature-tagged mutagenesis (STM) was applied to a previously established lung colonization model of infection by generating and screening a total of 1,800 mutants of an APEC strain IMT5155 (O2 K1 H5; Sequence type complex 95).

In this article, we report four sRNAs identified from the Xcc strain 8004 by generating and screening a cDNA library of low molecular weight RNAs, providing the first step towards an understanding of the function of sRNAs in Xanthomonas.

This study provides novel structure-function relationships for the periplasmic domain of the Campylobacter jejuni N-oligosaccharyltransferase PglB and describes procedures for generating and screening oligosaccharyltransferase mutant libraries in an engineered E. coli system.

In summary, this study adds important information to structure-function relationships of bacterial OST and provides methods for generating and screening OST mutant libraries in E. coli strains capable of producing engineered glycoproteins.

In total ~12,000 EMS-generated mutant lines were generated and screened for those that failed to complement either ATPalpha DTS1R1 or ATPalpha DTS2R3 null mutations for viability.

A peptide library was generated and screened in a microarray format for protein kinase-mediated phosphorylation.

Through computational product design, potential candidates can be generated and screened from a large pool of fuel blends.

Recently, a variety of improved methods have been developed to generate and screen this diversity more efficiently.

For validating the screening system, a mutagenic library of GOx from Aspergillus niger (EC 1.1.3.4) was generated and screened for improved activity using Saccharomyces cerevisiae as host.

This result highlights the importance of examining the possibility of temperature-dependent pore accessibility changes in 'designer' microporous materials, especially those generated and screened purely by computer13,47, to avoid substantial over-estimation of lower-temperature adsorption capacities.