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This fragmentation based WGA produces short 400-600 bp overlapping fragments that are primed with defined 3′and 5′ ends and amplified via linear amplification followed by geometrical amplification, therefore generating a thorough coverage of the genome.
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Once a variant list per sequenced CRC patient was generated, a thorough manual annotation using NCBI Gene corroborated variant genome position and annotated protein interactions.
In order to generate a thorough description of tissue OPs relevant to optical spectroscopy, however, broadband UV-Vis measurements are needed.
However, due to the large volumes of data generated, a thorough understanding of the biological and immunological significance of such information is often difficult.
The LiDAR- and DGPS-derived data generated a more thorough DEM than the 9″ DEM; however, LiDAR generated a surface topography that yielded significantly more detail than the DGPS survey, with no noticeable loss of elevational accuracy.
Much attention is currently being focused on the proteosome, a key component of the antigen processing pathway, and it is hoped that these studies will generate a more thorough understanding of antigen presentation, enabling us to design strategies to thwart this mode of immune escape [ 25].
Ian McHarg's "design with nature" theory contends that designers and planners should employ knowledge generated from a thorough ecological analysis of a place to guide actions.
Financiers believe that the most value added by a VC comes from carefully scrutinizing early-stage companies, generating leads, conducting a thorough due diligence process, and eventually investing the right amount of capital at the right valuation and structure.
Frank Rich's excellent historical and political analysis of the Bush administration's Iraq fiasco is significant enough to generate an in-depth, thorough debate of our Iraq policy as the very first order of business when Congress reconvenes next month.
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