Sentence examples similar to generating a pro from inspiring English sources

Upon activation through cell surface receptors such as TLRs, these dimers translocate into the cell nucleus and transcribe many genes involved in generating a pro-inflammatory response [30].

S100A4-positive fibroblasts produce VEGfibroblastsascin-C, which in turn contribute to generating a produceastatic environment [ 15].

NF- κB is strongly activated shortly after TNF engagement with TNFR1, generating a pro-survival signal that must be overcome in many cell types for TNF to induce apoptosis [ 31].

The results showed that the RE protocols for both chronic and acute training adopted by the authors did not generate a pro-inflammatory response.

The p38MAPK cascade would generate a pro-death output specifically in response to the expanded polyglutamine protein.

In this model the ERK cascade would generate a pro-survival signal in response to PKCι-mediated input.

In the case of sema3E the cleavage generates a pro-metastatic product that affects primarily endothelial cells rather than tumor cells [24] and is thus an example for an effect that will be seen only in-vivo but will not affect in-vitro assays such as the soft-agar colony formation assay.

Previous studies have demonstrated that the balance of cytokines is crucial to generate a pro-inflammatory response upon vaccination [ 16- 22].

The increased oxygen in the infarct heart modulated the post-translational profile and transcriptional activity of p53, in order to generate a pro-survival p53 type.

In this response, MLH1 appears functionally similar to other DNA damage-sensing proteins such as ICAD; cleavage of ICAD by caspase-3 generates a pro-apoptotic fragment that further increases apoptotic signalling (Tang and Kidd, 1998).

Thus, one possibility is that the activation of mitochondrial redox signaling in response to exposure to chronic mtDNA damage generates a pro-inflammatory environment that contributes to the aging phenotype in mutator mice.