Sentence examples similar to generating a high affinity from inspiring English sources

From this result, we demonstrated that our strategy was able to generate a high affinity molecule using only data in the training set.

The frequency of mature Tg+ B cells utilizing light chains that generate a high affinity anti-DNA antibody was determined.

Here we report the use of a T cell display system, using a retroviral vector, for generating a high-affinity TCR from the mouse T cell clone 2C.

Finally, these two potentially weak binders are chemically linked without perturbing their original binding poses with the hope of generating a high-affinity bidentate molecule.

Based on previous experimental and computational methods, we found a high affinity of the following residues with the channel: the neurotoxin 1BEI interacted with Arg11 and Dnp22, which was replaced from a Lys22 to generate a higher affinity; meanwhile the neurotoxins 2K9E and 1ROO interacted with Lys22, indicating its importance to the blockade of Kv1.3 channel pore.

In conclusion, our study designed a method to prepare human recombinant HE4 with high yield and generated a high-affinity anti-HE4 monoclonal antibody that might have potential for basic research and clinical application.

To construct a new recombinant immunotoxin for possible clinical use in patients with Hodgkin's lymphoma, we have chosen the murine anti-CD30 hybridoma Ki-4 to generate a high-affinity Ki-4 single-chain variable fragment (scFv).

To establish severe experimental NMO rat model closer to NMO pathomechanism, we used an AQP4-IgG derived from a baculovirus display method to generate a high-affinity and highly concentrated monoclonal IgG that specifically recognizes the extracellular domains of AQP4, and used it in the NMO/EAE model, after which we performed a detailed pathological examination in the acute phase.

We were able to claim that the generated molecule was a high affinity molecule because it appeared as such in the testing set.

Also, the major product generated by the sialyltransferase ST6GAL1 has a high affinity for other lectins, SNA, SSA, and TJAI, that showed preferential binding to pluripotent cells (, Lectin Frontier Database).

Finally, SLE-derived anti-chromatin autoantibodies showed a high affinity for apoptotic blebs generated by cold-shock.