In the presence of curvilinear structures, the included tracing tool can automatically follow the structure (Fig. 1b) and generate a fit from the projected profile (Fig. 1c).
With the GTPase domain, neck and trunk docked, application of the helical parameters (rise = 3.1926 Å, rotation = 63.815°) to the asymmetric unit generates a fitted model of the complete helical filament.
Results of this study showed that GRDi is a robust approach for generating a better fit and producing more reliable and accurate estimation of TBM downtimes compared to conventional statistical methods (R2 = 0.849).
In many situations, such as the interface is moving, the challenge is how to solve such a problem accurately, robustly and efficiently without generating a body fitted mesh.
With that in mind, a second approach was developed that read the experimental cumulative distribution of throat radii and generated a best fit to the original shape of throat radius distribution.
OsiriX then generated a T2 fit map graph with regression line and values for T2 and M0.
In contrast, in children demonstrating a sustained response, positive selection seems to accelerate viral evolution to generate a more fit population.
The functional form is flexible enough to pass much closer to these points though doing so generates a worse fit to these data.
An alternative approach to fitting these data sets would have been to use an optimization method in which all rate constants may be simultaneously adjusted to generate a best fit to all the experimental data.
Some architectures reproduced the observed gene expression data remarkably well (e.g., architecture 4, Figure 6C), whereas for other architectures it was impossible to find parameter sets that generated a good fit.
