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One of the main challenging issue is related to the intermittent production that generates serious problem in the power grids operations.
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The faster and faster global growth of energy consumption generates serious problems on its supply and about the pollution that may result.
However, burning of biomass fuel in a boiler has generated serious air pollution problem due to inappropriate boiler operation and inefficient dust collection system.
The anticipated rapid increase in the global human population, which is expected to reach 9.1 billion by 2050, might generate serious food shortage problems.
Considering all non-positive samples as negative samples not only can cause a high imbalance between both classes, generating serious model fitting problems [ 64], but because many genes most probably have functions yet not annotated, this procedure does not minimize the chance of including false negatives in the training set.
The Swedish government has tightened the criteria for obtaining asylum in Sweden since June 2015 because the large inflow of refugees had generated serious social and financial problems.
"Any contact should generate serious concern".
Step 4. Generating the three ontologies: One serious problem when generating an ontology from a Web page, the folksonomy data or the personomy data is its very large number of terms.
On the small scale needed for the production of a microarray, diffusion of the acid generated at an electrode to neighboring electrodes becomes a serious problem.
Indeed, Connecticut has serious problems generating adequate municipal revenue to pay for things like education.
Management of medical wastes generated at different hospitals in Egypt is considered a highly serious problem.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com