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Summarizing recent data on the rate at which the treatment of influenza infection generates resistance de novo and on the transmission fitness of resistant virus, we discuss possible implications for the epidemiological spread of drug resistance in the context of an established population dynamic model.
The large amount of defoliation caused by the high winds from typhoons also generates resistance to breakage and uprooting.
The lack of similar benefits in nerve-injured mice suggests that ongoing chronic pain generates resistance to the beneficial effects of environmental enrichment on mood.
It is hypothesized that the optimal resource allocated to immune function, which generates resistance towards parasites and reduce the fitness losses caused by parasitism, is depending on other requirements for energetic resource and the benefits associated with them.
However, this treatment generates resistance and toxicity, either by the side effects caused by cisplatin (neurotoxicity, myelotoxicity, nephrotoxicity and ototoxicity) or the side effects caused by radiotherapy (damage to the normal tissue).
Massoud, et al. [ 22] demonstrated the importance of the SA pathway in phosphite induced resistance in Arabidopsis against Hyaloperonospora arabidopsidis, while Eshraghi, et al. [ 23] and Machinandiarena, et al. [ 16] reported that potassium phosphite generates resistance via excessive accumulation of hydrogen peroxide and PR1 expression in Arabidopsis and potato, respectively.
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And they use coercive measures that generate resistance.
Bringing a disparate group of retail and investment banks under one roof may generate resistance.
But those efforts -- and the squeeze on doctors as health plans shrink payments for in-network care -- are generating resistance, experts say.
The hardship and inequality of the process have frayed tempers in austerity-hit countries and generated resistance – and partial non-compliance – which in turn have irritated the leaders of countries offering the "rescue".
Such measures could create positive pressure to deliver, avoid the "mission creep" that occurs when organisations chase funding to sustain themselves, and reduce the self-preservation biases that generate resistance to change.
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