GlyR α3K RNA editing leads to proline-to-leucine substitution (P185L) in the ligand-binding domain and generates gain-of-function neurotransmitter receptors.
"Some managers don't think they can generate gains to offset these losses," Mr. Phillips said.
Successful buyers generate gains in both revenue growth and profit margins, and — most important — better returns.
According to Meredith Jones of Van Hedge Funds, a research group, these funds shone last year, generating gains of as much as 17.1%.
Vaughn, they say, is being lined up for a villainous-sounding businessman who is trying to generate gains from the railway deals, while Farrell, Moss and Kitsch would play the detectives.
Given that the stock has been trading around $19 this week — it closed yesterday at $18.80 — Mr. Mozilo has generated gains of roughly $4 million in the last three days.
Better to buy the panels, install them free and then charge for the electricity they generate, gaining a predictable revenue stream.
Other big leveraged buyouts, such as Toys RR" Us and HCA, appear to be on track to generate gains, if largely on paper, for their owners.
"They may sell some securities to generate gains at the same time they're taking impairment charges," noted Dwayne D. Hallman, senior vice president for finance at Horace Mann Educators, an insurer in Springfield, Ill.
Despite the large amounts of data generated, gaining mechanistic insights and using the data for predictive and practical purposes is still a huge challenge.
Combining fronts may generate gains from "package deals," in which success on a single front yields a resource (such as capital, intellectual property, a valuable customer, a powerful ally) that is worth most when combined with other, similar resources.
