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The reason is simple: a distribution of selection coefficients generates dynamics dominated by strong driver mutations, whose effect is substantially larger than the mean (Park et al. 2010).
Another approach is to compare the fitness or marker dynamics generated by population genetic models with different underlying DFE and to try to identify the type of DFE that generates dynamics most closely resembling that of the observed data.
Starting out from an initial state, the reiterated application of equation (1) generates dynamics in which genes go through transient states until the whole network enters into a stationary or periodic profile of multi-gene expression.
Provided that the model is implemented with a particular connectivity, it generates dynamics that are consistent with the experimental results of biased competition (Reynolds et al., 1999), i.e. the dynamics show the level of competition and attentional biased up- and down-regulation observed experimentally in V2 and V4.
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In the first analysis, stochastic model simulations were parameterized from published empirical relationships and used to generate dynamics of phytoplankton communities reared under nitrogen-limited conditions.
"Climate change is generating dynamics and we see the tremendous results in terms of intensity, frequency, and magnitude of these natural effects, as we have just seen in Mocoa," he said.
In this context, it is important to emphasize not only structural and economic features, but also the cultural and social aspects that can generate dynamics of oppression and injustice.
The switch in the spike generating dynamics, observed experimentally as a change in the PRC type, may be an important factor in this change.
85, 110 Furthermore, traditional SIR models with strong cross-immunity generate dynamics inconsistent with pneumococcal carriage rates.
However, our observation that intranigral inhibition is strong relative to the major source of feed forward input suggests that local processing of diverse streams of information in the SN could be critical for generating dynamics in the basal ganglia output.
In this paper, we deal with a fundamental question in the development of multicellular organisms: How can biochemical reactions and genetic mechanism acting on the scale of minutes in individual cells generate dynamics with characteristic times of years to decades on the tissue level?
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