Sentence examples for generates abortive from inspiring English sources

Thus, the central region of both the ΨCTD and CTD plays a role in the transition from an initiating polymerase, which generates abortive RNAs, to an elongating enzyme, which produces full- length mRNAs.

This approach both enriches for the 3′ portions of any fragmented RNA's from the original samples and generates abortive transcripts whose sequence is biased toward the 3′ end of the original mRNA.

We postulate that these RNAs were generated from abortive initiation.

Alternatively, many genetic studies have highlighted the necessity of salvaging tRNA species from prematurely released peptidyl-tRNAs generated through abortive elongation events during protein synthesis, a function normally provided by a freely soluble PTH (reviewed by Das and Varshney, 2006).

Before transitioning to a stable elongation complex, steric clash between the elongating RNA transcript and elements of σ set up abortive initiation, where the RNAP repeatedly generates and releases short transcripts without dissociating from the promoter (McClure et al., 1978; Murakami et al., 2002a; Goldman et al., 2009).

Our results indicate that each flagellar beat cycle generates torque that produces either a productive or an abortive roll.

Although 2/3 ΨCTD could sustain cell growth, it generated increased levels of abortive transcripts.

DNA ligases can generate DNA damage through abortive ligation that produces chemically adducted, toxic 5′-adenylated DNA lesions, (e.g. adenylated 5′ ends containing ribose), which is characteristic of RNase H2 incision.

Nascent transcription in cells containing the 1/3 ΨCTD generated even higher levels of abortive transcripts.

Alternatively replication stress and stalled replication forks may trigger generation of abortive topoisomerase II complexes.

In contrast, p53-deficient cells exposed to SP600125 undertook a series of abortive mitoses (featuring karyokinesis but no cytokinesis), eventually generating giant cells that finally underwent apoptotic cell death.