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Sifting the most relevant and highest quality papers from this potential wealth of knowledge generates a significant challenge.
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Such knowledge and tools have generated a significant challenge for scientists: to design and conduct research studies that account for individual genetic variation.
An import price shock generates a significant decline in productivity.
Throwing a baseball generates a significant amount of stress across the elbow and shoulder.
Generating bioenergy is a significant challenge in reducing the environmental impact of fossil fuel combustion and in sustaining energy and energy independence.
Pluripotent stem cells (PSC) provide insight into development and may underpin new cell therapies, yet controlling PSC differentiation to generate functional cells remains a significant challenge.
To date it remains to be a significant challenge to generate sufficient biologically functional β-cells to replace damaged or malfunctional β-cells.
To generate novel or insightful hypotheses from this enormous quantity of data is a significant challenge.
Owing to the sheer quantity of data generated, the visualization, analysis, and interpretation of 3D imaging MS data remain a significant challenge.
Despite the availability of numerous crystal engineering techniques, generating drug-rich microparticles with a predetermined size, morphology and crystallinity still represents a significant challenge.
However, it remains a significant challenge to distinguish between the role of floral signals in generating or maintaining reproductive isolation vs. simply improving reproductive fitness in sympatry.
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