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Comparing with the direct Langevin algorithm, the new method generates a modified Markov chain by incorporating the coarse-scale information of the problem.
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As an example of the notation's utility, it is used to generate a modified earned value approach that weights quantities according to their position in a project's timeline.
In this report, we generated a modified high-fidelity version of base editor 2 (HF2-BE2), and investigated its base editing efficacy in mouse embryos.
To demonstrate the feasibility of this approach in elucidating the cause of outbreaks from hitherto novel or unknown viruses, we generated a modified NT database from which all sequences corresponding to the Orthomyxoviridae family had been removed (Fig. 8A).
Final models were generated using a modified protocol from Lindert et al. Twenty thousand decoys were generated using a simultaneously combined BCL EM-Fold and the memBCL EM-Foldn protocol in BCL::MP-fold.
Random gene-trees with edge lengths and pseudogenization vertices were generated using a modified version of PrIME-Gene-Tree generator [ 26] with pseudogenization rate of 0.5, and biologically realistic duplication-loss rates observed by analyzing gene families of OPTIC dataset [ 27].
Bulk ATAC-seq libraries were generated using a modified protocol based on previous study18.
Bathymetric contours at 10-m intervals were generated from a modified 10-m bathymetric surface.
Irregular particle arrangements within the reactors are generated by a modified ballistic deposition method.
We propose compliant cellular material (CCM), a mechanical metamaterial, with compliant porous structure (CPS) generated from a modified hexagonal topology.
Nuclei were loaded at ~120 nuclei/µl (5 10 µm capture sites, small chip) and RNA-seq libraries generated using a modified SmartSeq protocol containing both a supplemental random primer and PolydIdC as described previously10.
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