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It generates a gain of 45% for the combined macro and pico edge users at a very small cost for the cell centre lower than 4%.
In a heterogeneous network (HetNet) deployment, it generates a gain of 45% for the combined macro and pico edge users at a very small cost for the cell centre lower than 4% when compared with standard resource allocation.
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Mutation of this residue to asparagine, however, generates a gain-of-function phenotype.
Any new LSG generated should typically be initially non-essential, unless its genesis generates a gain-of-function essential phenotype in rare instances.
Alternatively or additionally, the pH-dependent BL-induced BRI1LRR-BAK1LRR interaction may also be associated with conformations of the residues surrounding BAK1Asp122 that generates a gain-of-function phenotype when mutated to asparagine.
Mutation of ALK at position 1174 F1174II) generates a gain-of-function receptor capable of activating intracellular targets such as ERK (extracellular signal regulated kinase) and STAT3 (signal transducer and activator of transcription 3) in a ligand-independent manner.
We determined the importance of this spatial restriction of HH signaling activity by generating a gain-of-function model in which HH signaling is ectopically activated in the cortical ureteric epithelium.
Initially, reports suggested that disease-related mutations in SPT1 generated a gain-of-function mechanism in SPT resulting in increased cellular glucosylceramide levels (7).
To further address the role of GASP1 during mouse development and in adulthood, we generated a gain-of-function transgenic mouse model that overexpresses Gasp1 under transcriptional control of the human cytomegalovirus immediate-early promoter/enhancer.
That would have generated a gain of more than $1 million.
Tyco, a diversified manufacturing and services company, said the sale would generate a gain of about $300 million.
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