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This notion has been refuted since the replacement of H295 with glutamine, an amino acid residue that cannot be protonated, generates a fully functional transporter with transport kinetics that are close to those of the wild-type EAAC1.
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Our studies show that a single Pro substitution at the middle of the dimer interface β-strand is sufficient to generate a fully functional monomer.
Here, we show that our approach was successful in generating a fully functional and easily detectable endogenous PC-1.
From this study, we have shown that it is possible to generate a fully functional microsatellite library from LCN aDNA templates.
We report here that our approach was successful in generating a fully functional and tagged endogenous PC-1 that can easily be tracked in vivo.
This study shows that RPK1 does not primarily control SAM genes, even the extreme rpk1-7 phenotype retains the capacity to resume shoot meristem development (eSM) and to generate a fully functional plant.
Reviewer #1: The authors have generated a fully functional YFP-tagged version of the ETS domain transcription factor Yan and studied Yan protein dynamics in the Drosophila eye disc during differentiation of photoreceptor and cone cells.
Basic users get a fully functional app for nada.
This experimental model holds great promise for the subsequent identification of the cellular, stromal and extrinsic signals necessary to specify, initiate, generate, and maintain a fully functional mammary gland population, and has been extended to include cells from other adult organs.
Here, we undertook steps to generate a new fully functional, highly expressed mouse CL Pgp that will serve as an improved tool for biophysical studies of the Pgp transport mechanism.
The institutional arrangements of the child care system suffered several changes which generated delays and bottlenecks, while the a fully functional governance of child care system require clear mandates and responsibilities with stable relationships among different levels of the system (central and local, state and non-state).
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CEO of Professional Science Editing for Scientists @ prosciediting.com