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This generates a double mystery: how did a theorist so smart end up saying such silly things?
Interestingly, as we follow the solution back up along the downward peak, the orbit segment generates a double step in the ADP, as shown in Figure 3d; we selected the orbit segment with the longest double step (with respect to time).
Treatment of the topo II-DNA complex with strong denaturants like SDS generates a double strand DNA break with denatured enzyme covalently attached to 5'-ends.
The homing endonuclease generates a double strand chromosomal break within the unoccupied target sequence.
This DSB repair mode ultimately generates a double Holliday Junction (dHJ) intermediate, which can be resolved by endonucleolytic cleavage to form either CO or non-CO products (Fig. 1).
This step generates a double bond between the C-4 and C-5 positions of the uronate residue, allowing UV detection of the generated fragments at 232 nm with an approximate molar absorption coefficient of 5500 M−1 cm−1 [ 36].
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The RNA-guided endonuclease Cas9 generates a double-strand break at DNA target sites complementary to the guide RNA and has been harnessed for the development of a variety of new technologies, such as genome editing.
Since these chosen depictions are almost iconic, quoting from them with alterations that are explicitly construed as political, generates a double-take and immediate scrutiny from the viewer.
The phagophore encloses a portion of the cytoplasm, which generates a double-membraned structure, the autophagosome.
Extension and repeated cycling generates a double-stranded product, akin to that generated in the annealed oligo method.
Briefly, the HEG is expressed and intron/HEG mobility is initiated when the site-specific homing endonuclease (HE) generates a double-stranded DNA break at or near the site of insertion in an intron-less allele, soon after mating between intron-containing and intron-lacking organisms [e.g., [ 16, 17]].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com