Sentence examples for generated to specifically from inspiring English sources

Nestin-Cre mice, expressing Cre recombinase under control of the rat nestin promoter and its CNS specific enhancer, were initially generated to specifically inactivate the glucocorticoid receptor (Gr) gene in the nervous system [4].

DR-specific agonistic antibodies and rhTRAIL variants have been generated to specifically target one TRAIL death receptor to enhance efficacy (Ichikawa et al, 2001; Kelley et al, 2005; Pukac et al, 2005; van der Sloot et al, 2006; Adams et al, 2008; Li et al, 2008; Tur et al, 2008; Reis et al, 2009, 2010).

A peptide to the amino-terminus of PKAc (CAT 1-29) was generated to specifically disrupt the interaction between AKIP 1A and PKAc to study nuclear import of the complex.

In order to better define the length and boundaries of interstitial regions that were identified as deleted or amplified with the CGH 44A Microarray, a custom array was generated to specifically interrogate these regions at a higher resolution.

MB504B is a Split GAL4 line we generated to specifically label four individual dopamine neurons in the PPL1 cluster: MB-MP1, MB-MV1, MB-V1, and the neuron that projects to the tip of the α lobe.

It is thus possible that PINK1 senses localized mitochondrial damage or damaged mitochondrial subcompartments in a manner similar to that by which it regulates mitophagy via mitochondrial import deficiency, but rather than degrade the entire organelle, MDVs are generated to specifically remove the damaged segments.

Despite the fact that our gene expression signature was generated to be specifically associated with CK5/14 positivity, it clearly also recognizes a distinct set of CK5/14-negative tumors.

Answering such questions and establishing robust metrics is difficult due to the lack of publicly available RNA-seq data specifically generated to capture gene fusions.

Although this is an important caveat in the interpretation of our data, these mice were specifically generated to model the global variation in 5-HTT expression seen in humans, which is not restricted to the amygdala.

To generate tools to specifically interrogate the functions of GPN2 and GPN3 we created mutant alleles of each gene using a mutagenic PCR approach described previously (Ben-Aroya et al. 2008).

Indeed there were relatively few matches to ESTs from libraries generated specifically to study nacre building gene sets in Haliotis asinina and the bivalve Pinctada maxima (6,122 and 6,737 ESTs respectively) indicating the divergence in biomineralisation processes between these two different molluscs [ 56].