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Notably, some of these small transcription "noises", which were once regarded as the degraded remnants, have been demonstrated to be generated through specific pathways and play essential roles in plant development (Chen, 2009).

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A national study however reports that programme information generated through disease-specific M&E systems is not necessarily made available to district managers [ 33].

Kimba mice, generated through photoreceptor-specific overexpression of human VEGF165 protein, demonstrate retinal neovascular changes, increased permeability, pericyte and endothelial cell loss, vessel tortuosity, leukostasis, and capillary blockage, dropout and hemorrhage (Tee et al., 2008).

Lipid rafts function as contributors to lateral membrane heterogeneity and are generated through lipid lipid and specific lipid protein interactions.

Aptamers can be generated through SELEX to target specific molecules with advantages over antibodies.

OLs are generated through a series of specific developmental stages (Pringle and Richardson, 1993; Ono et al., 1995), during which they are exposed to a range of signalling factors that can be inductive or inhibitory, extracellular or intracellular (Miller, 2002).

During evolution, the development of complex eukaryotic organisms such as Volvox is generated through selective expression of specific fraction of the same genome in different cell types in response to developmental and environmental cues [ 59, 63].

The problem specific knowledge generated through the rigorous application of the optimal control theory is used to formulate the set of decision variables representing the qualitative and quantitative aspects of the feed rate profile.

AP sites are generated through spontaneous depurination or lesion specific enzymatic hydrolysis of the N-glycosyl bond between the deoxyribose and base.

A diverse promoter library could also be generated through random mutagenesis using a specific promoter as template (Alper et al. 2005).

Additional insights into the role of Brg1 in muscle [ 13, 14], mammary epithelium [ 15], smooth muscle [ 16, 17] and myeloid [ 18] differentiation have been generated through the studies of a specific point mutation (K798R) in the ATP-binding domain of Brg1 that act via a dominant-negative (dn) mechanism [ 19].

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