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Increased radical production has been attributed to the presence of NPs even in the absence of radiation which can cause damage to the cellular components due to ROS being generated (Pan et al. 2009) triggering first the apoptosis and as a consequence the necrosis of the cell (Xia et al. 2006).
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Using a polymorphism-based definition of the pseudo sequence (see Materials and Methods), we were able to generate pan-specific predictors of comparable predictive performance to that of predictors defined using the structure-based definition (data not shown).
Hence, it provides a challenging opportunity to assess the potential of our pipeline to generate pan-legume family anchor markers.
This study focused on generating pan-genomic cDNA microarray data for diverse xenograft models from the time of initial implantation to the tenth passage using the Affymetrix HG-U133 Plus 2.0 array.
This fragmented group II intron has thus existed for a long time and has provided sequence variation, on which selection can act, contributing to diverse genetic rearrangements, and to generate pan-genome divergence after strain differentiation.
Consistent with this assumption, we found that the insertion of the ancient RmInt1-like intron into the ancestor of pSymA has, to some extent, contributed to generate pan-genome divergence after strain differentiation.
To this end, we generated the pan genome and core genome plots once again.
Using the same partitioned bins as described above, we also compared the recombination rate with the genomic double-strand break (DSB) map generated by Pan et al. [ 18] (using immunoprecipitation of Spo11-bound oligos in meiotic SK1 cells).
By mutating the sequence of this ligand, a "secondary" library was generated, whose panning on HER2-positive cells isolated a phage-borne peptide with increased specific binding to HER2 (phage NL1.1).
Here we report the creation of just such a large and diverse collection of Ab fragments binding MPs, generated by panning phage-displayed libraries of single-chain antibodies (scFv) on whole cells.
The innermost circle is the generated reference pan-genome against which each prophage genome is compared.
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