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Researchers have routinely generated new strains of mice by manipulating mouse embryonic cells, and some aspects of this technology may prove useful for improving human embryonic cells.
Indeed, we generated new strains deleted for RGP1 or RIC1, encoding components of the Ypt6 GEF complex (Siniossoglou et al. EMBO J, 2000).
As suggested, we generated new strains and looked for a potential co-localization of Sec7 and Vps17 in the rod1 Δ and the gga1Δgga2Δ mutant strains.
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Fredrickson says toward the end of his book that racism in the United States is "like a bacillus that we have failed to destroy, a live germ that not only continues to make some of us ill but retains the capacity to generate new strains of a disease for which we have no certain cure".
On the other hand, a high immune and antiviral drug pressure in the host population pushes the influenza virus to mutate rapidly to generate new strains of IAV.
The use of modified codons ensures maximal expression in the host and eliminates the possibility of recombination with influenza viruses that might potentially generate new strains.
The results reveal a novel plasmid that is devoted almost entirely to carriage of these two biosynthetic pathways and indicate not only new mutasynthesis pathways but a paradigm for generating new strains that combines the products of different pathways and creates more potent bioactive molecules.
Occasional co-infection in wildfowl could generate new strains incorporating Tamiflu-resistant NA genes.
First, partial escape from cross-immunity recurrently generates new strains with beneficial mutations, which carry new epidemics.
Virulence of virus strains could be regulated through interaction between herd immunity, introduction of naïve individuals, and ability of virus to shed and to generate new strains [ 5].
For example, 200 generations of artificial selection for reduced ethanol and enhanced glycerol yields of Saccharomyces cerevisiae were enough to generate new strains showing little to no decrease in fermentation activity (Tilloy et al. 2014).
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CEO of Professional Science Editing for Scientists @ prosciediting.com