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Dataset B (Mnaimneh et al. 2004), generated more recently, consisted of 215 expression profiles from yeast cultures with titratable promoters of genes essential for cell survival.
Therefore, those exons would have been generated more recently, probably within the past 40 ~ 50 million years, by exon duplication, while the other exons would already have existed, and would have continued to evolve by point mutations.
Thirdly, previous comparative analysis of SDs in four primate genomes indicated in particular that those located in the distal halves of LCR22-2 and LCR22-4, were generated more recently.
Since large SDs overall show low sequence divergence as described above (Additional file 1, Figure S1), this result further suggests that the bulk DNAs constituting these three blocks was likely generated more recently during evolution than other LCR22 blocks.
Stable transgenic mutant lines of zebrafish sod1 (G93Rameshmeth et al., 2010; Sakowski et al., 2012) have been generated more recently, including useful sod1 (G93R and G85R) heat-shock reporter lines (McGown et al., 2012).
The bulk of the present-day species diversity is likely to have been generated more recently, with the crown nodes of the two principal subclades being dated to 3.6 Ma (clade A: 1.2 – 7.0 Ma) and 4.2 Ma (clade B: 1.5 – 7.9 Ma), consistent with a role for post-uplift scarp erosion.
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Independent inventors are not common, but they have generated more significant products than you might think, even recently: Beanie Babies, the computer mouse, Kitty Litter, Odor-Eaters.
They generated more belief.
Across our study's 20 mammals, exaptation of ancestral DNA generates more of the recently evolved regulatory genome than do repeat-driven expansions.
Half a dozen price cuts haven't done much to generate more traffic — two months recently passed between showings — and the Schneiders are now asking $874,900.
SeaWorld said the California lawsuit was "clearly a publicity stunt intended to generate more news coverage" of a recently-published book about the park by John Hargrove, a former SeaWorld Trainer.
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