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Point mutations were generated integrated into the genome as described (Schulz and Zakian, 1994; Ribeyre et al, 2009).
To further investigate each pathway, we have generated integrated KEGG maps with differentially expressed genes identified in the different studies.
We generated integrated quantitative transcriptome maps by systematic meta-analysis from any available gene expression profile dataset related to AMKL in pediatric age.
In an effort to reconcile our results with those of Kwon et al. (2010), we generated integrated transgenic strains expressing either daf-16a or daf-16f under the control of their native promoters.
As a control, we also generated integrated versions of Lac1 and Lag1 in which Ser23 and Ser24 were mutated to Glu, to mimic conversion of the entire population to the phosphorylated state, a response that we showed can be achieved for the wild-type protein (see, for example, Figure 3B).
Indeed, both JoinMap and MergeMap generated integrated maps with good consistency in marker order (measured by Spearman's rank correlation coefficient r) compared with component population-specific maps for most LGs (JoinMap, r > 0.90 for all three pairwise comparisons for 11 LGs; MergeMap, r > 0.95 for the three pairwise comparisons for all 19 LGs).
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A new seismic campaign has been designed and acquired, and a single, geologically consistent geophysical model has been generated integrating the existing and new data.
A set of algorithms exist to generate integrated development environment (IDE) command recommendations.
The dynamic missions are simulated using commercial software to generate integrated loss-of-mission (LOM) probability results via Monte Carlo sampling.
Surface electromyography (EMG) was measured bilaterally for 5 shoulder and 3 low back muscles and processed to generate integrated muscle demand for each combination evaluated.
The establishment of temporary local administrative organizations may be an effective solution to break cross-sector barriers and generate integrated solutions to realize environmental objectives.
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