Germline-derived pluripotent stem cells (gPS cells) can be generated by induction of pluripotency in mouse unipotent germline stem cells without the introduction of exogenous transcription factors.
In this study we focused on cholinergic neurons generated under induction of NGF.
Curious of the molecular function of cohesin recruitment to DSBs, the authors designed an elegant experiment to test whether functional cohesion was generated after induction of DSB.
In comparison with the effect of other proinflammatory cytokines, IL-17 generated stronger induction of IL-6 and IL-8 than did IL-15 or IFN-γ.
To show that ssDNA oligos generation is a physiologically relevant phenomenon, we sought to establish whether ssDNA oligos could be generated following induction of chromosomal breakage.
It remains to be determined whether UV-B-induced ROS are generated via induction of a NADPH oxidase activity by CDPK.
Some of the puncta should represent autophagosomes because they were positive for the autophagosomal SNARE STX17 (syntaxin 17) (Fig. S1A), but others might be ubiquitin-positive SQSTM1 aggregates, which may be generated by induction of SQSTM1 (Fig. S1B).
To investigate the effect of MSeA treatment on tumor growth, an animal model was generated by induction of xenograft tumors using MDA-MB-231 cells in athymic nude mice.
Cumulative concentration response curves for acetylcholine (Ach; 10-9 M to 10-4 M) and sodium nitroprusside (SNP; 10-9 M to 10-4 M) were generated after induction of an approximately 60% contraction with phenylephrine (Phe) of maximal contraction caused by 31.4 mM KCl.
The introduction of c-Myc with other transcription factors (including SOX-2) generates the induction of pluripotent stem cells from differentiated cells [ 40].
