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We examined in mathematical models the equilibrium NTHi-caused AOM rate given hypothetical vaccines that generated immunity identical to corresponding maximal naturally acquired immunity.
Using these chimeric mice we were able to effectively isolate iBALT generated immunity from that generated by conventional secondary lymphatic tissues.
An ideal antigen generated immunity without causing disease.
Given these considerations, it has been surprising that pre-immunocompetence solid tissue transplants have almost universally generated immunity [ 2, 3, 14- 20] or putative ignorance [ 18] rather than tolerance.
Active immunisation of patients with HER-2/neu peptide-based vaccines (also including HER-2(15369)) generated immunity to HER-2/neu peptides and to HER-2/neu intracellular and extracellular domains (Disis et al, 2002).
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This suggests skin-immunization generates immunity less efficiently [124], [128], or increases intrinsic parasite infectivity [124], [128], [131].
Sublethal amounts generate immunity, and antibodies are obtained from the plasma of the immunized animal.
All these results suggest that immunization with tobacco leaves expressing SAG1 is a reliable system to generate immunity, which could be boosted by heterologous prime-boost inoculation regimens.
In the meantime, however, the process by which the body reacts against infectious organisms to generate immunity became better understood.
The vaccine was found to generate immunity with levels of antibodies increasing over a period of 28 days.
Normally, influenza vaccines are made by culturing live virus in hens' eggs, a risky and time-consuming procedure, but the new method was simpler and it produced a vaccine that appears to generate immunity to a wide range of flu viruses rather than being restricted to just one strain, scientists said.
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