Sentence examples for generated immune responses from inspiring English sources
The personalized vaccine induced CD4+ T-cell responses targeting neoantigens in 8 out of 10 people who received the personalized vaccine and generated immune responses that were evaluated.
After treatment, 39% of patients generated immune responses to the vaccinating peptide.
In fact, MM cells can present recall antigens to the immune system (Mutti et al, 1998), and systemic administration of IL-12 generated immune responses to MM in murine models (Caminschi et al, 1998).
The humoral and cellular responses suggest that the VLP containing fusion constructs generated immune response in a Th1 dependent manner.
Studies in mouse models suggest that CCL21 secreting tumors may alter the locally generated immune response by promoting tumor-induced tolerance, which facilitates tumor progression [ 51].
Similarly, plasmid encoding Japanese encephalitis virus premembrane and envelop genes generate immune responses and induction of protective immunity against Japanese encephalitis in mice [ 15].
"If we can prove that it works, it will be a game changer for how we think about generating immune responses against cancer," says Figlin.
Taken together, our data demonstrate that dtSCT DNA vaccines coexpressing a universal CD4 epitope are highly effective in generating immune responses to poorly processed and presented cancer antigens.
Thus, inclusion of an immunogenic capsular component as well as protective antigen in new anthrax vaccines would generate immune responses targeting both the bacteremic and toxigenic aspects of anthrax infection and thus may increase protective efficacy.
Patients who have GVHD that is refractive to these agents may be treated with a monoclonal antibody, which is designed to bind to and block specific targets involved in generating immune responses.
