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STPA handles safety as an emergent system property and specifically investigates risks generated by functional interaction between system components.
Our results suggest that PCNA ubiquitination and ATR activation are two independent events that occur in response to a common single-stranded DNA intermediate generated by functional uncoupling of mini-chromosome maintenance (MCM) helicase and DNA polymerase activities.
The algorithm, called Helios, was used to analyze a combination of genomic data and information generated by functional RNAi screens, enabling them to predict several dozen new SCNA drivers of breast cancer.
When the contaminant underwent the same reconstitution process, no tubular structures were formed (Fig. S4D), further confirming that the tubules we observed could only be specifically generated by functional PbYOP1 proteins.
However, in the absence of structural changes, tactile hypoaesthesia might be generated by functional impairments of sensory pathways, namely a central inhibition of non-noxious pathways [14].
The present work demonstrates a novel method for quantitatively measuring the contractile stress generated by functional cultured skeletal muscle using a Bio-MEMS device, which can selectively stimulate the contraction of a myotube and simultaneously record the physiological behavior in real time.
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Abstract: We consider trace functions generated by the functional calculus of a real function and obtain a complete characterization of the class of geodesically convex trace functions of this form.
We consider trace functions generated by the functional calculus of a real function and obtain a complete characterization of the class of geodesically convex trace functions of this form.
For a full interpretation of the data generated by the functional analysis in IPA we used the "effect on function" feature in IPA, which allowed determining among those significantly-enriched functions, which specific sub-function/s, tissue, or cellular component/s affected the function and in which direction (i.e., increase/decrease the function).
Comparative analysis of the results to verify the accuracy of the data generated by (a) functional mode and by (b) the discrete- and real-time modes Table 1 Workload parameters for functional validation.
In FDA, an outlier is defined as an observation generated by a functional random variable with a distribution that is different from the one generating the observations of a functional sample13.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com