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What's more, the decimation of the revenue streams once generated by analogues of recorded music have put paid to many a musician's income.
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Electrical discharges in Martian analogue materials have previously been generated by agitation of the material in a low-pressure carbon dioxide environment.
In the course of our investigations we decided to synthetically modify the parent compound to clarify the structural determinants responsible for the activity; in fact, very recently, our research group reported the synthesis and the pharmacological properties of a first collection of PM analogues generated by Ludi approach.
Losing the huge amount of noise generated by donepezil and its analogues more than compensated for their positive contributions to the final ranking.
The weak proapoptotic effects of clodronate that has been occasionally observed could be attributed to the accumulation of toxic analogues of ATP generated by bisphosphonate metabolism (Frith et al, 1997).
Inspired by the insights into the molecular basis for substrate specificity generated by our structural analysis of MccB, we sought to further probe the enzyme's substrate tolerance by investigating the precursor-directed biosynthesis of additional stambomycin analogues.
Libraries of aminocoumarin analogues have been generated by in vivo fermentation, via feeding known amide synthetase substrates into producing microbial strains.
Analogues of tiopronin were also generated by replacing the glycine with alanine, valine, serine, or phenylalanine; all retained selective activity, emphasizing that the thiol was indeed critical for activity.
Refinement parameters for the triazole ThDP analogue were generated by PRODRG2 (28).
To investigate the mechanism of antibacterial activity of this new chemotype, a resistant strain of S. aureus was generated by serially passaging the organism in escalating doses of the most active analogue.
As visual analogues of the spectral shape stimuli, rectangles of varying dimensions were generated by holding total flux (area) constant, while varying the height/length ratio.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com