Lenz and Becker [ 48] showed that PCR generated artefacts could constitute up to 25percentt of the alleles when no approach is taken to reduce artefact formation.
Studies of human designers have identified that the ability to generate artefacts that are novel, surprising, useful and valuable are facets of the human cognitive capacity for creativity.
Consequently objects such as intravenous lines, tubes or other devices generate artefacts in the adjacent sections, which may obscure the lung parenchyma.
In particular, repetitive and low-complexity sequence might generate artefacts in assembled supercontigs.
However, violation of assumption No. 2 alone should rarely generate artefacts that may be mistaken as remaining tumor tissue.
Cholesterol is present at levels of about 1000-fold higher than endogenous oxysterols and can generate artefacts by non-enzymatic autoxidation during sample preparation.
The background noise (including maternal ECG/PCG, movement-generated artefacts and external noises such as 50 Hz mains power) is concurrently captured.
This successfully removes >99.9%% of the cholesterol from the oxysterol fraction, whatever batch is used, greatly reducing the risk of generating artefacts by autoxidation.
How did you ensure that the acoustic signal did not influence the EEG signal which was used for detection of movement planning" This protocol did not generate artefacts as a consequence of the acoustic signal.
The poor overlap of results could be explained, at least in part, by preanalytical and analytical variables and donor-related factors that could generate artefacts, impairing an accurate quantification of circulating miRNAs.
Since, in our experience, and that of others, microsatellite instability is rare in breast cancers, we suspected that the multiple (35) rounds of PCR amplification required to obtain sufficient product from fixed tissue sections were generating artefacts.
