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For genomic data sets of size k = 2 to 40 in increments of 2, we generated affinity tables with 3000 rows and k - 1 columns.
Importantly, the anti-CII antibody response in mice, even antibodies that are pathogenic, are to a large extent germline encoded and thereby lack somatic mutated, generated affinity maturation [ 6, 7, 24, 25].
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To analyze LEKTI-2 protein expression, we generated affinity-purified polyclonal LEKTI-2 antibodies.
Using our newly generated affinity-purified polyclonal anti-Geminin antibody G95, we found little to no expression of this repressor of origin licensing during G1 phase, with detectable levels at the G1/S transition and increasing linearly during the remainder of the cycle before mitotic degradation.
Convolutional networks can learn to generate affinity graphs for image segmentation.
We have developed the use of archaeal extremophilic proteins as scaffolds to generate affinity proteins (Affitins).
After Wolf's death, in 2011, Raja wrote a short essay to commemorate her dear friend, inspiration, and mentor: The assiduous study of the words of an author generates affinity, closeness.
It is anticipated that thermally stable variants will serve as excellent scaffolds for generating affinity reagents to a variety of targets of interest.
We describe concepts and methodologies for generating "Affinity Clamps," a new class of recombinant binding proteins that achieve high affinity and high specificity toward short peptide motifs of biological importance, which is a major challenge in protein engineering.
These methods have been very successful in generating affinity reagents by searching large libraries of oligonucleotides, small protein domains, or small peptides, to identify a few reagents with high affinity for the target.
Monoclonal antibody technologies, phage display and mRNA display, are methods that could be used to generate affinity ligands against each member of the proteome.
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