Granule cells have a thin, poorly myelinated axon that generates a small population of enormous terminals [58], [59].
Support for this hypothesis is provided by the strong evidence that spontaneous differentiation of ESCs in vitro consistently generates a small population of germ cells within 3 5 days of culture [27], [28], [29], [30], [31], [32], together with the result that conditional loss of Pten in fetal germ cells invariably causes teratomas from the abnormal germ cells in vivo [33].
A fraction of cells surrounding the dorsal root entry zone migrate into the formed DRG and generate a small population of TrkA-positive neurons [ 34].
This was somehow expected since the F2 population generated a smaller number of recombinant meioses compared to MARC map.
The cancer stem cell (CSC) theory implies that tumours are generated and maintained by a small population of cells with both self-renewal and differentiation properties that contribute to tumorigenesis and cancer cell heterogeneity.
"But while we have a landmass half the size of Wales, we have the population of a small English village, which generates a lot of responsibilities for a small population.
On the other hand, a small population will generate only a subset of all possible 1-step beneficial mutations, with few mutations that confer large fitness effects [ 13, 15, 16].
Thus, we cannot rule out that there may be a small population of circular RNA generated via a direct backsplice mechanism, as previously reported in vitro (Pasman et al., 1996; Schindewolf et al., 1996).
Explicit tests of the point were made here by asking if stimulation of a small population of mossy fibers generates a CA3 population event with the characteristics of a SPW.
In that view, what looks very unlikely in a small population of birds to generate beak shapes that go from pliers to forceps seems not so remarkable.
