Exact(29)
Starting from such conceptual design, we generated a library of 4-substituted azabicyclo[5.3.0]alkane Smac-mimetics.
Fan et al. generated a library of variants of a fungal chitinase after three rounds of error-prone PCR and DNA shuffling.
Another advantage of this method of using a synthetic catalog long enough to represent all considerable earthquakes is that we generated a library of seismograms.
In this study, we generated a library of IGF1R deletion and point mutants to examine IGF1R subcellular localization and activation of downstream signaling pathways.
We generated a library of 108 Sso7d mutants by randomizing 10 amino acid residues on the DNA-binding surface of Sso7d, using yeast surface display.
Herein, we have successfully generated a library of allosteric inhibitors against FBPase as potential anti-diabetic drugs, of which, the lead compound 1b was identified through utilizing a virtual high-throughput screening (vHTS) system, which we have developed.
Similar(31)
The least number of oligonucleotide primers, electroporations and ligation reactions were used to generate a library of 1.5 × 108 individual clones, without generation of sub-libraries.
These reaction patterns will be used for generating a library of molecules accessible to prenylation.
These results provide a new fluorination strategy to generate a library of highly efficient and non-cytotoxic polymeric gene vectors.
The method is also applied to generate a library of reduced kinetic models for an adaptive chemistry simulation of a 2-D laminar, partially-premixed methane burner flame.
This latter method can be used to generate a library of diverse conformers, or like the other methods to seek a low energy conformer [36].
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