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That dynamic generated a background buzz of briefing and counter-briefing that routinely drowned out Ed's public interventions.
The binding site predictions are based on a position weight matrix algorithm and to compute the statistical significance, we generated a background sequence set of 10,000 randomly selected 500 bp sequences, roughly matching the 9002 binding sites identified in the PPARγ and RXR ChIP-PET experiments.
Every animal's pre-infection or pre-sensitization sera generated a background antibody response to SF-PPD antigens.
As a control, we repeated this analysis after reassigning the TFBR intensities randomly within each species to different loci, which generated a background expectation that assumes random divergence.
The vector pKKlux generated a background luminescence (212 RLU/10 s), which was identical to the luminescence caused by the P TK construct (210 RLU/10 S).
In brief, by simulating 10,000 random points followed by 3D distance measurements toward (1) the nearest chromocenter surface (defined as DAPI dense signals) and (2) the nuclear periphery (defined as edge of the DAPI signal), we generated a background distribution for each analyzed nucleus.
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A number of video-coding techniques also used the MoG-based approach to generate a background frame and use an additional reference frame to encode uncovered/occluded regions of a frame for better coding efficiency [72 75].
As the organs are evaluated in situ, the presence of uptake in surrounding or nearby tissues generates a background that reduces sensitivity compared to that obtained when the tissue is removed from the subject.
In addition, sources of radioactivity completely independent of the patient can generate a background radiation: for example, in LSO- or LYSO-based PET scanners, a small background of 176Lu radiation can be seen when the PET signal in the patient is extremely low, as in 90Y imaging.
No hypermutated sequences were identified at all indicating that the QT6 cell line did not generate a background editing signal (Figure 1C).
Therefore only a narrow region near the object plane of the observation objective lens is illuminated and fluorophores outside this plane are not excited and do not generate a background signal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com