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Previous work (Fonteijn et al., 2012) demonstrated the EBM's ability to order biomarkers and generate staging measures derived from imaging data, in genetically defined disease and control populations (familial Alzheimer's disease and Huntington's disease).
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During voltage recordings zebrafish spinal neurons generate stage-specific forms of activity [ 5 8, 15].
Intriguingly, this list includes several full-length Wolbachia genes with the potential to be functional that are also shown to generate stage-specific transcripts.
During the ' generate' stage, project teams ran stakeholder workshops in which invited healthcare professionals and managers co-created new service concepts.
For example, to generate stage 3 extracts from embryos developing at 23°C, packing and crushing was initiated exactly 1 hr and 40 min after fertilization and completed 20 min later, just before the second embryonic cleavage would have occurred.
Since the fer-1 alleles are temperature sensitive, animals used for assays were synchronized by the hypochlorite method then grown at the restrictive temperature of 25°C to generate staged young adults.
Indeed, the rigid timescale of differentiation and division is the key for generating staging patterns because a wide range of differentiation and division time creates asynchronous cohorts of germ cells and disrupts stages.
Once stable plasma was generated, stage was turned on to move sample into the plasma field for the desired exposure time for the pre-deposition surface activation treatment.
Timelines were revised in the light of additional facts or insights generated (stage 3).
Afterwards, the polyploidy cells evolve in malignant clonal cell expansion generating stage 4S or stage 4 NB, each of which is characterized by distinct genomic features.
In addition, employing an exponential distribution for progression in order to relate specified TTP parameters to their corresponding EPD values, the model generates stage I stopping rules using easily calculable RR and EPD rates.
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CEO of Professional Science Editing for Scientists @ prosciediting.com