These include steps towards improving crystallization of protein protein complexes, identifying the clusters of residues that constitute putative small molecule binding 'hot spots', generating new methods for detecting the binding of small molecules to target proteins, and generating custom libraries via diversity oriented synthesis to enable the identification of natural-product-like hits.
Improving our understanding of the biology of these vectors (and recognizing the differences between them) is important in generating new methods of control at a time when there is emerging resistance of the mosquito to insecticide and resistance of the malaria parasite to drug treatment [ 54- 56].
The aim of the study was to use the DH Commissioning guidance [ 22] as a general framework, and where appropriate integrate existing evidence, and develop or use new methods to generate new evidence to populate a costed commissioning framework.
In other words, with the implementation of HPWS, employees acquire greater control of their work, feel more loyal to their companies, and therefore become more incentivized to optimize their working methods, generate new ideas and take risks.
Our development of an analytic technique for considering spatial and temporal access simultaneously using GIS methods demonstrates the potential for using these methods to generate new insights into a range of problems surrounding palliative care distribution and utilization.
In general it is defined as new applications of knowledge, ideas, or methods which generate new capabilities and leverage competitive sustainability [2,10,11].
This chapter focuses on procedural methods that generate new graphical objects by synthesizing geometry.
To answer this question, we used two methods to generate new phylogenies that accounted for homologous recombination in the core genome.
In contrast to these results, the lowest importance value emerged for domain 5 – presence of methods to generate new research to inform the organisation's work.
These supplemental empirical methods can generate new hypotheses and may stimulate the interest of toxicologists and basic scientists to investigate and explain the patterns reported.
