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Joinpoint regression was used to generate incidence trends by stage and subsite location.
Negative binomial and Cox proportional hazards regression modelling were used to generate incidence rate ratios (IRR) and HRs with 95% CIs, respectively.
While cross-sectional surveys such as Demographic and Health Surveys routinely gather 2-week point prevalence rates for low- and middle-income countries around the world, these data cannot be used to generate incidence rates because they can be highly affected by seasonal variation in incidence.
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For bed days, we used negative binomial models to calculate log mean differences and generated incidence rate ratios.
Using Poisson regression in EPICURE software [ 16], we generated incidence rates and rate ratios (RRs) via standard likelihood ratio methods [ 17].
Mid-year population estimates from the Department of Statistics were used to generate crude incidence and age-standardized incidence rates [ 5].
The geographic population at risk for illness that should be used as a denominator to generate disease incidence figures might be considerably different than the population from which the ICU admits its patients.
Classic mathematical models of tumor development developed by Armitage and Doll (Armitage and Doll, 1954; Hornsby et al., 2007) suggested that 5 8 rate-limiting events are required to generate such incidence patterns.
As used in previous studies [ 5], and because CLA-BSIs are rare events, a Poisson regression analysis was used to generate an incidence rate ratio (IRR) compared with baseline CLA-BSI rates (Stata software, version 10; Statacorp, College Station, TX, USA).
As AFE is infrequent, the most robust studies of the condition are population-based studies, ideally incorporating large numbers of pregnant women in order to have sufficient statistical power to generate stable incidence estimates and examine a range of risk factors to assess the independent risk associated with each.
As used in previous studies [ 9], and because CLABSI are rare events, a Poisson regression analysis was used to generate an incidence-rate ratio (IRR) compared with pre-intervention CLABSI incidence density rates.
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