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This explosion of biomedical resources generates impediments for the biomedical researchers' needs, in order to efficiently discover appropriate resources to accomplish their clinical tasks.
Checkpoint mutants fail to detach transcribed genes from nuclear pores, thus generating topological impediments for incoming forks.
In Agile, the role of the manager is to enable those doing the work to contribute their full talents and capabilities to generate value for customers and eliminate any impediments that may be getting in the way.
Because fork advance and the progression of the transcription bubble generate positive supercoiling, a head-on collision between replication and transcription causes topological impediments and fork pausing (Liu and Alberts, 1995; Olavarrieta et al., 2002; Wang, 2002).
Another major impediment is the lack of information and methodological tools to generate plausible scenarios that can reliably inform strategic decision-making [ 17].
Generate, generate!
To overcome this impediment, we generated an experimental copy of the Tex11 gene at an autosomal locus, placing a Tex11 knockin allele under the transcriptional and translational control of Tex19.1 (Chr. 11; Fig 2A).
To determine whether mex3-1 knockdown resulted in a global impediment in generating postmitotic cells, we quantified the proportion of piwi-1−PIWI-1+ cells, which are thought to represent immediate stem cell progeny that have permanently exited the cell cycle.
This generates confusion and may create unintended impediments for research.
The revenues to states' coffers generated by racing are one of the impediments to developing a national, centralized racing governance.
The report also singled out the legal system for its reliance on generating revenue from mostly poor citizens as one of the key impediments to serious reform.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com