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A major use of results from subgroup analysis is to generate hypothesis for future clinical trials.
The purpose of the models is to test and generate hypothesis of specific pathways and it is therefore required to estimate model parameters from experimental data.
Computational approaches have made key contributions to perform efficient analyses of data, filtering compounds collections to select molecules for experimental screening, generate hypothesis to understand the mechanism of action of drugs, and the design of new chemical structures.
They argue for a cyclical process of 6 steps: 1) watch/discuss, 2) generate hypothesis, 3) develop code, 4) apply code, 5) analyze/interpret, and 6) link to video, before going back to watching and discussing again.
Additionally, we developed a target-adverse effect model to be applied to the drug-target predictor with two purposes: to generate hypothesis about drugs, targets and adverse effects, and improve drug-target identification.
Novel approaches are needed to both infer the causal genes and generate hypothesis on the underlying regulatory mechanisms.
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For example, the comparison of ChIP-seq profiles lets labs generate hypotheses about differential binding.
The ability to generate hypotheses is essential to creative, imaginative, divergent thought.
Biologists use a technique called cladistics to assemble 'family trees' of organisms and generate hypotheses about their relationships.
During recognition, the ratios of triplets of regions are used as indices to generate hypotheses.
This allows GREAT to generate hypotheses about the regulatory functions of the set of genomic regions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com