Sentence examples for generate hotspots from inspiring English sources

It is therefor unclear what threshold for automatic hotspot identification and segmentation that is optimal in order to generate hotspots that best reflect true tumor burden.

We describe how a small number of single-base-pair substitutions can generate hotspots de novo and dramatically alter their distribution in the genome.

The frequency with which spontaneous mutations generate hotspots de novo is likely high enough to support rapid evolutionary change because the reservoir of cryptic DNA sequence motifs is vast.

The aggregation of plasmonic particles can induce a shift in the localized surface plasmon resonance and generate "hotspots" of high local E field intensity, making aggregation a popular way to increase SERS intensity.

Mutation of cryptic DNA sequence motifs within ORFs can generate hotspot-active DNA sites (Schuchert et al. 1991; Virgin et al. 1995; Steiner et al. 2009), but more often than not such mutations will also alter the sequence of the encoded protein or lead to premature termination of protein synthesis.

For the case of planar multilayer hyperbolic metamaterials, the absorption enhancement is expected to be a weak effect due to the lack of any localized plasmons which generate field hotspots [83].

In other cases, it is not very straightforward, because, when multiple radiating sources generate a hotspot in a cumulative manner, sources do not coincide with the hotspot position.

This does not mean, however, that V-sRNAs generated from hotspots were more efficient than other V-sRNAs since recent studies have shown that transgenic plants programmed to express dsRNAs corresponding to the most targeted region did not guarantee resistance against Tomato chlorotic mottle virus (ToCMoV) infections [50].

In addition, selection by species on each other may be strongly reciprocal in some populations, generating coevolutionary hotspots, and not in others, producing coevolutionary coldspots [ 3, 4].

We applied multiple importance thresholds (cut-offs) to separately identify and measure social and ecological hotspots, and then quantified the degree of spatial concurrence (overlap) when combining the layers to generate social-ecological hotspots.

It is surprisingly easy to alter the strength of coevolutionary selection to generate relative coevolutionary hotspots and coldspots in our laboratory populations.