Exact(28)
To generate conditional alleles, genes are commonly engineered to contain recognition sites for bacteriophage recombinases, such as Cre recombinase.
We showed that this somatic CRISPR-Cas9 technology provides a quick and efficient approach to generate conditional knockouts in various cell types at different developmental stages.
In particular, by following a geostatistical approach, we study the idea of monitoring the cumulative contaminant mass extracted from the installed recovery wells, and using these measurements to generate conditional realizations of the hydraulic conductivity field.
With the recent characterization of multiple cilia proteomes along with efforts of several consortia to generate conditional alleles of all genes in the mouse, further use of conditional mutation approaches promise to yield many advances and surprises as we explore the functions of this increasingly complex organelle.
CAGGFP-Spry1 female mice were bred with Tie2-Cre male mice to generate conditional transgenic mice.
We applied Cre/loxP system to generate conditional gene targeted mice that allow inactivation of critical components of Notch signaling pathway in the skin.
Similar(32)
The genotypes Pdx1-Cre:Kras G12D/+ (termed KC mice) and Rage −/− were crossed to generate conditional-mutant mice (Pdx1-Cre:Kras G12D/+ : Rage −/− ) termed KCR mice.
It makes use of trajectory splitting for generating conditional samples.
Bragg scattering of the atoms from an optical lattice generates conditional evolution in the external degrees of freedom of the atoms.
To examine the physiological functions of OGR1, we generated conditional OGR1 deficient mice by homologous recombination.
In the present study, we have generated conditional knockout mice for each B-raf alternatively spliced exons.
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