Sentence examples for generate cell death from inspiring English sources

On the other hand dephosphorylated Bad interacts with Bcl-xL a pro-survival molecule, and inactivates it to generate cell death [ 29].

The results presented here indicate that the oncogene Bcl-xL exploits the inherent stochastic nature of molecular events to generate cell-death variability, which transforms a single-cell discrete event like death into a graded population response and leads to adaptation.

The benefit that could generate programmed cell death in a unicellular organism has been deeply discussed [ 39].

Therefore, we treated OA chondrocytes with sodium nitroprusside (SNP), which is known to generate chondrocyte cell death.

In most experimental models of AMI, the duration of the index ischaemic episode is selected so as to generate 50% cell death or an MI size of 50% of the area-at-risk (AAR).

Not surprisingly, this highly selective inhibitor cocktail generated widespread cell death within 2 days of treatment.

Apoptotic breast cancer cells transfected with ANT2 shRNA also induced a cytotoxic bystander effect that generates necrotic cell death to the neighboring cells.

Interestingly, retina damage caused by different concentrations of ouabain generates extensive cell death of retina neurons and promotes the surviving Müller glia to proliferate robustly within a 3- to 12-day period [ 54].

The emerging view is that the modified forms of autoantigens generated during cell death might stimulate autoantibody responses if presented to the immune system in a proinflammatory context [ 40].

TLRs are the best characterized 'pattern recognition receptors' that recognize conserved microbial molecules and mediate immune and inflammatory cellular responses to infection and microbial products and in some cases responses to endogenous factors generated during cell death, inflammation, and tissue damage.

If mTOR is persistently activated, too much ATP will be consumed and too much ROS will be generated, leading to cell death.