Whatever the nature of these additional functions is, our results argue that Bub1 depletion perturbs monopolar attachment by generating merotelic attachment of paired sister kinetochores, like Sgo2 or Ark1 depletion.
This may be due to the charge on the nickel-histidine complex which would inhibit close association of the J3 antibody fragments to generate multivalent attachment to the gp140 on ELISA surface.
Through this process of building an environment that welcomes all levels of players, clubs generate "emotional attachment and loyalty," two crucial elements that help get Chinese kids on the field.
In the absence of fibrin (e.g. in the Col4a1+/Svc mouse), the fibroblasts in the BM-denuded areas of tendon appear to generate opportunistic attachments with overlying structures.
The Dam1 complex has been proposed to generate these attachments by partnering with the kinetochore-localized Ndc80 complex (Shang et al, 2003).
In addition to providing evidence that the Ska complex functions to generate kinetochore microtubule attachments, Theis et al suggest that it may have an additional function during mitosis.
These kinetochores can generate microtubule attachments through capture of centrosome-derived microtubules, but in addition, they can generate microtubules themselves, which are subsequently integrated with centrosome-derived microtubules to form the mitotic spindle.
These results suggest that the Ndc80 complex is not sufficient to generate kinetochore microtubule attachments in eukaryotic cells, and the Ska complex joins the ranks of essential players in this process.
The ability to influence the shape of an object automatically generates emotional attachment.
This generates an attachment site for the Fbw7 E3 ubiquitin ligase, resulting in polyubiquitinylation and c-Jun degradation [10].
