Sentence examples for generate a rationale from inspiring English sources

These findings help to explain the clinical efficacy of anti-CD20 therapy in most patients in clinical trials and generate a rationale for the use of anti-CD20 therapy in a broad population of MS patients.

Overall, these findings generate a rationale for the use of anti-CD20 therapy in a broad population of MS patients and show that B-cell depletion is comparable to the efficacy of more traditional T-cell-directed therapy.

These studies have generated a rationale for the use of Syk inhibitors in the treatment of crystal-induced arthritis and other autoinflammatory diseases.

While the addition of ICR62 to either afatinib or gemcitabine had no additional growth inhibitory effect compared with treatment with a single agent, a synergistic effect was observed in five of the seven human pancreatic tumour cell lines when afatinib was used in combination with gemcitabine (Table 2), thus generating a rationale for assessing such combination in vivo.

The goals of the in vitro α-glucosidase and α-amylase inhibitory studies were to provide in vitro evidence for the potential inhibition of α-glucosidase and α-amylase and to generate a stronger biochemical rationale for further studies on 50% ethanolic extracts of O. stamineus leaves.

As a proof of concept, we have applied this rationale to generate a site-selectively dual labelled superfolder green fluorescent protein.

However, the aim of this pilot study was to provide novel data to support the underlying rationale and generate a sample size for a subsequent experimental trial.

His obsession is doing deals, analysts say, and the rationale is to generate a buzz for Star's role in the initial public offering.

Here, we extend the optogenetic toolset by developing a neuromodulatory approach using a rationale-based design to generate a Gi-coupled, optically sensitive, mu-opioid-like receptor, which we term opto-MOR.

On the basis of this rationale, we decided to generate a live cell tool to discriminate apoptosis and necrosis.

This rationale was used to generate a comparator group "clean" of possible CAD.