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This work challenged the paradigm that transcription was generally regulated at Pol II recruitment and initiation.
These results globally suggest that the enzyme stimulation observed after the humic supply may be generally regulated at the transcriptional level.
As glycosyltransferases are generally regulated at the level of transcription, assessing the overall transcriptional profile for glycan biosynthesis genes seems warranted.
Since Puma expression is generally regulated at the transcriptional level, we examined Puma mRNA levels by quantitative RT-PCR.
The determination of TF activity is difficult since it is generally regulated at the protein level and thus undetectable by transcription profiling.
Although lipoprotein lipase (LPL) activity is generally regulated at the post-transcriptional level in adipose tissues (e.g. [ 53]), allowing rapid responses to alterations in diet, LPL mRNA levels correlate with PPARγ mRNA levels in epididymal WAT [ 54] and increase with PPARγ agonist treatment [ 55], likely due to a transcriptionally active PPAR response element upstream of the LPL gene [ 56].
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This suggests that some genes may be preferentially regulated during cellular adaptation to its environment, while some genes are generally not regulated at a transcriptional level.
Therefore, it could be hypothesized that other poikilothermal animals are hosts of L. monocytogenes, although virulence genes appear generally down regulated at low temperature [ 63].
The SROs are able to interact with transcription factors through the C-terminal RST domain but themselves are generally not regulated at the transcriptional level.
Generally, "regulated" meant "controlled" and "ordered" by some power or authority.
When such tenants vacate an apartment, its rent is generally regulated by the rent stabilization laws.
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