This practice works relatively well for lumped modeling applications when the accuracy of sub-watershed processes is generally not of concern.
Third, the authors assumed that hypercalcemia was "generally not of concern" and did not consider possible effects of hypercalcemia on costs or effectiveness.
Conflicts of interest in surgery, and in healthcare generally, are of concern because they have the capacity to skew decision making in ways that might possibly, but not necessarily, impact patient care adversely.
In one survey [ 11], 57% of physicians reported that their patients were reluctant to take corticosteroids long term and their patients agreed: almost 50% and 70% were apprehensive about taking ICS and oral corticosteroids, respectively, generally because of concern over long-term side effects associated with these drugs.
The losses are generally of little concern to the companies themselves, because most of the tuition is paid by federal loans backed by the taxpayer.
The power of the different tests for publication bias is generally of great concern.
Measures of identity and stability are generally of less concern to researchers growing hESCs than are the potency and undifferentiated state of the cells.
But what is particularly tiresome is that it has really caught on in the liberal press, as sexism is not generally an issue of concern to conservatives.
However, in practical terms reservoirs generally only become of concern when disease control within the target population reduces transmission within a target population to a very low level relative to transmission from nontarget to target populations.
However, the higher frequency of injection site reactions in the ID formulation is mostly related to erythema, swelling and pruritus, and these adverse events are not generally a cause of concern for patients [ 29], while the frequency of pain, the most troublesome symptom, is low and comparable to that caused by IM administration [ 15, 30].
