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EGFR and KRAS mutations were generally mutually exclusive; these exclusivities were significant for the Western/ADC (Pcorr = 1.8 × 10−36) and Asian/ADC (Pcorr = 1.9 × 10−27) subgroups.
These HR defects include mutations in the HR pathway genes RAD51C, RAD51D, and PALB2 (6–10%)7,9,10, as well as methylation of BRCA1 (7–17%)7,11,12 or RAD51C (1.5–3%) promoters11,13, which is generally mutually exclusive of BRCA1/2 mutation7,9,10.
Mutations in KRAS and BRAF are generally mutually exclusive, implying equivalent downstream effects in tumorigenesis [13].
These mutations are generally mutually exclusive.
KRAS and BRAF mutations are generally mutually exclusive in colorectal tumors [ 44].
Our data confirmed that mutations in these genes were generally mutually exclusive.
Similar(44)
Altogether there is generally a mutually exclusive distribution of EFL and EF-1α, and both are scattered around the tree of eukaryotes.
Seven to 17% of metazoan genes have tandem exon duplications (Letunic et al. 2002; Gao and Lynch 2009), generally associated with mutually exclusive alternative splicing (Kondrashov and Koonin 2001; Irimia et al. 2008).
Pleasing editors and writing the truth as I see it, I generally find, are not mutually exclusive.
Improvement of muscle peak power and oxidative capacity are generally presumed to be mutually exclusive.
The presence of EML4 ALK generally seems to be mutually exclusive of the presence of EGFR or KRAS mutations in NSCLC [ 1, 7, 8].
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