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These results highlight the role of non-conserved regions in SH3 target selection, and introduce a strategy that may be generally feasible for generating artificial SH3 domains with desired ligand binding properties.
Although early studies of quantitative traits also revealed clues about such networks[ 6], it has not been generally feasible to address the more general questions how they originate and evolve.
Our study points out that the self-rating STEP questionnaire was generally feasible and accepted by a majority of older patients, in a routine general practice setting.
A simple test simulation proves that the 1-dimensional model coupled with a commercial CFD software is a generally feasible technique.
When composites are employed as structural materials, joining of composites to other materials is necessary because manufacturing structures with composites only is not generally feasible.
Overall, it is generally feasible to arrange rail transit transportation with speed below 200 km/h on the cantilever deck of the Shanghai Yangtze River Bridge.
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Experimental research of drug safety in pregnancy is generally not feasible because of ethical issues.
Due to the lack of distinct characteristics, it is generally not feasible to unequivocally identify personal care products as source of microplastics detected in the environment.
One criticism of renewal processes is that they are not generally "multilocus feasible" in the sense of Liberman and Karlin (1984).
As the cost of numerical simulation can be very high it is generally not feasible to couple the simulator directly to the optimizer.
However, imaging at 48 h was generally not feasible with the activities (approximately 148 MBq) and emission times (typically 6 to 8 min per bed position) used in this study.
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