Until 1915, that was the generally accepted determining factor for sex.
An increased risk in cigarette smokers [ 2] represents the only generally accepted such factor [ 3].
In the next step clinical response was deleted, because it is not a generally accepted prognostic factor within all working groups, because it is judged to be investigator dependent.
Because histological grade is the most important, generally accepted, prognostic factor in soft tissue sarcomas as well as in chondrosarcoma, the predictive value of VEGF may be less important in those tumours than that in conventional osteosarcomas that are exclusively high grade in histology.
"Puzzling," the Aberdeen Evening Express declared, noting that Morris's studies failed to take into account what were then generally accepted risk factors for heart attack, such as a temperamental propensity toward "nervous strain".
The purposes of this study were as follows: (1) to determine the prevalence of osteoporosis in patients with severe PPH before lung transplantation, (2) to investigate whether generally accepted risk factors for osteoporosis would play a role in this special group of patients, and (3) to determine whether there is an association between functional parameters and pretransplantion bone mass.
Generally accepted prognostic factors for endometrial carcinoma are nodal involvement/stage, grade, and histologic subtype [ 55].
The univariate variables were then entered into a multivariate Cox model including age, sex and histologic subtype, as they are generally accepted prognostic factors.
Studies have found differing degrees of association between radiographic changes and pain severity, but it is generally accepted that factors other than radiographic features contribute to pain levels.
We found associations for the generally accepted risk factors for postmenopausal breast cancer (i.e., family history, benign breast disease, education, age at menarche, duration of hormonal replacement therapy) (Table 2).
